Bryan L Roth Selected Research

Caveolin 1

11/2009	Caveolin-1 and lipid microdomains regulate Gs trafficking and attenuate Gs/adenylyl cyclase signaling.
8/2004	Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors.

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Bryan L Roth Research Topics

Disease

27	Schizophrenia (Dementia Praecox) 01/2023 - 12/2001
17	Pain (Aches) 12/2023 - 01/2005
7	Catalepsy 10/2017 - 06/2006
6	Substance-Related Disorders (Drug Abuse) 06/2023 - 01/2005
6	Respiratory Insufficiency (Respiratory Failure) 01/2023 - 01/2016
6	Parkinson Disease (Parkinson's Disease) 01/2023 - 12/2008
6	Obesity 01/2018 - 12/2001
6	Psychotic Disorders (Schizoaffective Disorder) 01/2014 - 01/2004
5	Hallucinations (Hallucination) 06/2023 - 06/2013
5	Bipolar Disorder (Manic Depressive Psychosis) 01/2011 - 09/2002
4	Migraine Disorders (Migraine) 09/2023 - 06/2015
4	Neoplasms (Cancer) 01/2017 - 02/2009
3	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2023 - 12/2001
3	Central Nervous System Diseases (CNS Diseases) 01/2023 - 02/2006
3	Neuralgia (Stump Neuralgia) 12/2021 - 11/2013
3	COVID-19 01/2021 - 01/2020
3	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2019 - 12/2008
3	Mental Disorders (Mental Disorder) 01/2012 - 10/2006
3	Heart Valve Diseases (Valvular Heart Disease) 11/2011 - 06/2003
3	Weight Gain 04/2011 - 03/2003
2	Pruritus (Itching) 05/2024 - 01/2023
2	Cluster Headache (Cluster Headaches) 09/2023 - 01/2023
2	Leukemia 01/2022 - 01/2011
2	Hypersensitivity (Allergy) 12/2021 - 11/2013
2	Opioid-Related Disorders (Opiate Addiction) 01/2021 - 01/2014
2	Infections 01/2020 - 11/2004
2	Carcinogenesis 01/2019 - 07/2014
2	Hyperglycemia 01/2019 - 03/2003
2	Schistosomiasis (Bilharziasis) 12/2017 - 01/2016
2	Prader-Willi Syndrome (Syndrome, Prader-Willi) 02/2017 - 08/2010
2	Hyperalgesia 01/2016 - 11/2013
2	Chronic Pain 01/2016 - 12/2001
2	Anxiety Disorders (Anxiety Disorder) 02/2014 - 05/2010
2	Neurodevelopmental Disorders 12/2011 - 03/2010
2	Dementia (Dementias) 03/2011 - 09/2002
2	Myeloid Leukemia (Leukemia, Myelocytic) 01/2011 - 06/2008
2	Glioma (Gliomas) 11/2009 - 08/2004
2	Hypertension (High Blood Pressure) 07/2009 - 03/2003
1	Hemorrhage 12/2023
1	Cardiotoxicity 11/2023
1	Pulmonary Arterial Hypertension 10/2023
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 09/2023
1	Heart Failure 01/2023

Drug/Important Bio-Agent (IBA)

16	Antipsychotic Agents (Antipsychotics)IBA 01/2018 - 03/2003
13	LigandsIBA 11/2023 - 08/2010
13	Serotonin ReceptorsIBA 01/2022 - 12/2001
10	Opioid Analgesics (Opioids)IBA 01/2023 - 09/2002
9	Serotonin (5 Hydroxytryptamine)IBA 01/2022 - 12/2001
8	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2023 - 01/2010
8	GTP-Binding Proteins (G-Protein)IBA 06/2023 - 01/2015
8	Analgesics (Analgesic Drugs)IBA 01/2023 - 01/2014
7	Hallucinogens (Psychedelics)IBA 09/2023 - 11/2009
5	Opioid Receptors (Opioid Receptor)IBA 01/2023 - 03/2012
5	Morphine (MS Contin)FDA LinkGeneric 01/2021 - 01/2016
4	Lysergic Acid Diethylamide (LSD)IBA 09/2023 - 01/2020
4	Anti-Anxiety Agents (Anxiolytics)IBA 06/2023 - 11/2009
4	ArrestinIBA 01/2023 - 01/2016
4	Antidepressive Agents (Antidepressants)IBA 01/2019 - 11/2009
4	Clozapine (Clozaril)FDA LinkGeneric 01/2016 - 04/2005
4	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 10/2011 - 09/2003
3	Psilocybin (Psilocibin)IBA 09/2023 - 01/2020
3	Histamine (Histamine Dihydrochloride)FDA Link 01/2021 - 07/2008
3	Dopamine (Intropin)FDA LinkGeneric 10/2017 - 02/2004
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 08/2004
3	salvinorin AIBA 10/2006 - 09/2002
2	Phosphates (Orthophosphate)IBA 05/2024 - 10/2005
2	LipidsIBA 12/2023 - 11/2009
2	Ethanol (Ethyl Alcohol)IBA 06/2023 - 01/2023
2	LisurideIBA 06/2023 - 01/2023
2	Nicotine FDA Link 06/2023 - 01/2023
2	Dopamine Receptors (Dopamine Receptor)IBA 01/2023 - 01/2018
2	EnzymesIBA 01/2022 - 01/2020
2	Histamine Receptors (Histamine Receptor)IBA 01/2021 - 08/2020
2	Famotidine (Pepcid)FDA LinkGeneric 01/2021 - 08/2020
2	Oxycodone (Oxycontin)FDA LinkGeneric 01/2021 - 01/2021
2	kappa Opioid Receptors (kappa Opioid Receptor)IBA 01/2019 - 09/2002
2	5-HT2C Serotonin ReceptorIBA 01/2018 - 08/2010
2	Praziquantel (Biltricide)FDA Link 12/2017 - 01/2016
2	Amphetamine (Amfetamine)FDA LinkGeneric 10/2017 - 01/2016
2	lorcaserinIBA 10/2017 - 12/2013
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2017 - 02/2011
2	Serotonin 5-HT2 Receptor AgonistsIBA 10/2017 - 01/2016
2	Haloperidol (Haldol)FDA LinkGeneric 01/2016 - 09/2014
2	Peptides (Polypeptides)IBA 03/2015 - 12/2014
2	pimavanserinIBA 12/2013 - 12/2008
2	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 03/2011 - 03/2003
2	Caveolin 1IBA 11/2009 - 08/2004
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 02/2006 - 01/2005
1	Dinoprostone (PGE2)FDA Link 12/2023
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 12/2023
1	ProstaglandinsIBA 12/2023
1	Ibogaine (Endabuse)IBA 11/2023
1	5-HT2B Serotonin ReceptorIBA 10/2023
1	Proline (L-Proline)FDA Link 01/2023
1	Antihypertensive Agents (Antihypertensives)IBA 01/2023
1	Guanosine Triphosphate (GTP)IBA 01/2023
1	Glutamine (L-Glutamine)FDA Link 01/2023

Therapy/Procedure

11	Therapeutics 09/2023 - 03/2003
4	Analgesia 01/2021 - 01/2015
2	Lasers (Laser) 01/2019 - 01/2019